Choline Salicylate + Lidocaine is a combination of two medicines: Choline Salicylate and Lidocaine. Choline Salicylate is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers (prostaglandins) which cause pain and inflammation (redness and swelling). Lidocaine is a local anesthetic. It works by blocking pain signals from the nerves to the brain which decreases the pain sensation.